CENTRAL SCIENTIFIC RESEARCH LABORATORY

644001, Omsk-1, 129,20 let RKKA str.

Medical Academy

Phone: (RUSSIA) 381 (2) 338-114

Head: Vasiliy V. Lobov, senior research worker, Cand. Sc.(Medicine)

Orientations of scientific research:

• study of the role of immune disturbances in the postresuscitation pathology of the central nervous system and working out of optimal ways of these disturbfnces immunocorrection;
• disturbances of mechanisms of visceral organs function regulation and compensation in postresuscitation period;
• study of the role of purine metabolism disturbances and conjugated stimulation of lipid peroxidation processes in brain and liver membrane structures damage in terminal states and postresuscitation period;
• working out, bench-testing and approbation of new hemosor- bents in the patients with systemic purulent diseases.

Publications:

1. Author's certificate 1802335.MKI A1GO1H33/60. A method of radiometric definition of phosphoribosilpyrophosphate content in biological tissues / V.D.Konvay, P.P.Zolin, G.G.Veitsman.
2. Blood serum protein spectrum of patients with acute peritonitis / B.A.Reis, V.D.Konvay, Yu.V.Redkin e.a. // Vestnik intensivnoi terapii (Bulletin of intensive therapy). - 1995. - N2. - P.36-40.
3. Effect of hemosorption on the level of medium molecular polypeptides mass and humoral immunity in the patients with peritonitis / L.V.Poluektov, Yu.V.Redkin, B.A.Reis e.a.// Vestnik khirurgii imeni I.I.Grekova (Bulletin of surgery). - 1988. - N4.- P.115-120.
4. Lobov V.V., Konvay V.D., Pospelov V.S., Bykhovtsev A.N. Effect of dioxyphenyl alanine on carbohydrate metabolism regulation in the postresuscitation period // Patologicheskaya fiziologiya i eksperimentalnaya terapiya (Pathologic physiology and experimental therapy). - 1993. - N3. - P.26-28.
5. Lobov V.V., Pospelov V.S., Tagiltseva M.P., Lukoshkin A.V. Effect of central nervous system on the erythron functional state during the rehabilitative period after the organism resuscitation // The International symposium " Central nervous system and postresuscitation pathology of the organism ": Proceedings. - Moscow,1989. - P.154-155.
6. Golovin A.A., Konvay V.D. Lipid peroxidation processes in iron deficiency anemia complicated with frequent catarhal diseases // Klinicheskaya meditsina (Clinical medicine). - 1991.- N11. - P.73-75.
7. Golovin A.A., Konvay V.D. The role of lipid peroxidation in iron deficiency anemia pathogenesis // Terapevticheskiy arkhiv (Therapeutic archives). - 1991. - N12. - P.38-41.
8. Golovin A.A., Konvay V.D., Redkin Yu.V. Metabolic and immunologic disturbances in pathogenesis of iron deficiency anemia and its complications // Klinicheskaya meditsina ( Clinical medicine ). - 1989. - N8. - P.64-65.
9. Golovin A.A., Konvay V.D., Redkin Yu.V. Mechanism of external respiration failure in the patients with iron deficiency anemia // Terapevticheskiy arkhiv (Therapeutic archives). - 1990. - N4. - P.53-55.
10. Golovin A.A., Redkin Yu.V., Sokolova T.F. Clinical- immunologic parallels in the patients with iron deficiency anemia // Terapevticheskiy arkhiv (Therapeutic archives). - 1988. - N10. - P.103-105.
11. Zolin P.P., Konvay V.D., Grishechko S.I. Homeostates in terminal states energetics // Homeostatics of alive and technical systems: Proceedings of the All-Union conference. - Irkutsk, 1991. - Part 1. - P.72-74.
12. Sokolova T.F., Redkin Yu.V., Pastukhov V.V., Rozhdestvensky M. Ye. Alteration of immune status in the workers of the Western Siberia region // Gigiyena i sanitariya (Hygiene and Sanitation). - 1993. - N3. - P.23-25.
13. Reis B.A., Redkin Yu.V., Sokolova T.F., Ktenidi L.I. Cellular factors of natural immunity in the patients with acute peritonitis // Anesteziologiya i reanimatologiya (Anesthesiology and reanimatology). - 1994. - N3. - P.17-20.
14. Konvay V.D. Liver purine exchange in the postresuscitational period // The Constituent Congress of the International pathophysiological society:Proceedings. - Kuopio,1991. - P.332.
15. Konvay V.D., Lukoshkin A.V., Pospelov V.S. Disturbance of hepatic glutathione exchange in resuscitated rats and its correction / Voprosy meditsinskoi khimii (Problems of medical chemistry). - 1988. - N1. - P.65-68.
16. Konvay V.D., Lukoshkin A.V., Pospelov V.S. Disturbance of hepatic purine exchange in resuscitated rats and its correction // Patologicheskaya fiziologiya i eksperimentalnaya terapiya (Pathologic physiology and experimental therapy).- 1987. - N5. - P.26-28.
17. Konvay V.D., Lukoshkin A.V., Smirnova V.B. The role of purine exchange disturbances in the progress of postresuscitation metabolic deviations // The 5th All-Union Biochemical Congress: Abstracts of the bench-testing reports. - Moscow,1986. - Vol.2. - P.97.
18. Konvay V.D., Reis B.A., Zolin P.P. The role of acute purine metabolism tailure in the postresuscitation disease pathogenesis // Actual problems and perspectives of the modern reanimatology progress. - Moscow,1994. - P.46-47.
19. Lobov V.V. Effect of pharmacological activation of monoaminergic regulating systems on visceral functions in the postresuscitation period // The Constituent Congress of the International pathophysiological society. - Kuopio,1991. - P.332.
20. Lobov V.V. Damage of histaminergic regulation mechanisms in the rehabilitation period after clinical death of various duration // Actual problems and perspectives of the modern reanimatology progress. - Moscow,1994. - P.38-39.
21. Lobov V.V. Neurophysiological and humoral mechanisms of blood circulation regulation in the terminal states // Krovoobrashcheniye (Circulation). - 1990. - N5. - P.3-7.
22. Lobov V.V. A new method of brain bioptates taking for the research of macroergic phosphates exchange // Patologicheskaya fiziologiya i eksperimentalnaya terapiya (Pathologic physiology and experimental therapy). - 1992. - N5-6. -P.56-57.
23. Lobov V.V., Bykhovtsev A.N. Vegetative-effector damages in the rehabilitative period after circulatory arrest of various duration // Patologicheskaya fiziologiya i eksperimentalnaya terapiya (Pathologic physiology and experimental therapy). - 1991. - N2. - P.23-25.
24. Lobov V.V., Bykhovtsev A.N. Monoaminergic and cholinergic mechanisms of cardic vascular responses regulation after circulatory arrest of various duration // Krovoobrashcheniye (Circulation). - 1991. - N1. - P.3-9.
25. Lobov V.V., Dolgikh V.T., Korpachyov V.G. The character of relationship between changes of intra- and extracerebral circulation during the rehabilitative period after resuscitation of the organism // Krovoobrashcheniye (Circulation). - 1986. - N4. - P.65.
26. Lobov V.V., Konvay V.D. Carbohydrate metabolism and conjugated processes regulation disturbances during the rehabilitative period after clinical death of various duration // Voprosy meditsinskoi khimii (Problems of medical chemistry). - 1991. - N4. - P.45-48.
27. Lobov V.V., Konvay V.D., Bykhovtsev A.N. Carbohydrate metabolism in the failure of monoaminergic regulatory mechanisms which progressing in the early postresuscitation period //Voprosy meditsinskoi khimii (Problems of medical chemistry). - 1992. - N5. - P.26-28.
28. Lobov V.V., Konvay V.D., Lukoshkin A.V. Effect of dexamethasonum on metabolism of hormones regulating carbohydrate exchange during the postresuscitation period // Farmakologiya i toksikologiya (Pharmacology and toxicology). - 1990. - N1. - P.53-54.
29. Lobov V.V., Lukoshkin A.V. Improvement of blood reinfusion technique in modelling of terminal states caused by blood loss // Patologicheskaya fiziologiya i eksperimentalnaya terapiya (Pathologic physiology and experimental therapy). - 1986. - N6. - P.77-78.
30. Lobov V.V., Lukoshkin A.V., Konvay V.D. Effect of dipiridamole on the course of rehabilitative period after circulatory arrest // Farmakologiya i toksikologiya (Pharmacology and toxicology). - 1988. - N2. - P.125.
31. Lobov V.V., Pospelov V.S., Bykhovtsev A.N. Effect of tryptophan on brain and blood content of regulatory neuropeptides and cyclic nucleotides // Problemy endokrinologii (Problems of endocrinology). - 1993. - N3. - P.45-47.
32. Lobov V.V., Pospelov V.S., Kazakova A.V. The character of neuroendocrine relationships in alteration of severity of central nervous system postresuscitation damage // Byulleten Sibirskogo Otdeleniya Akademii Meditsinskikh Nauk SSR ( Bulletin of the Siberian Department of the Academy of Medical Sciences of the USSR). - 1990. - N2. - P.50-53.
33. Lobov V.V., Suslova T.V. Thermoregulation failures during the rehabilitative period after clinical death // Anesteziologiya i reanimatologiya (Anesthesiology and reanimatology). - 1991. - N1. - P.26-30.
34. Lobov V.V., Tagiltseva M.P., Pospelov V.S., Kazakova A.V. Morphologic alterations and cytochemical leucocyte profile in disturbances of glucocorticoid secretion regulation in the postresuscitation period // Patologicheskaya fiziologiya i eksperimentalnaya terapiya(Pathologic physiology and experimental therapy). - 1991. - N4. - P.14-17.
35. Poluektov L.V., Reis B.A., Philippov S.I., Ktenidi L.I. Pathogenetic substantiation of hemosorption in complex peritonitis management // Byulleten Sibirskogo Otdeleniya Akademii Meditsinskikh Nauk SSSR (Bulletin of the Siberian Department of the Academy of Medical Sciences of the USSR). - 1987. - N2. - P.33-37.
36. Pospelov V. S., Lobov V.V. Effect of extracorporal attachment of the donor spleen on the vegetative function of the organism during the postresuscitation period // Byulleten Sibirskogo Otdeleniya Akademii Meditsinskikh Nauk SSSR (Bulletin of the Siberian Department of the Academy of Medical Sciences of the USSR). - 1988. - N4. - P.30-32.
37. Redkin Yu.V., Sokolova T.F. Pathomorphologic aspects of immunologic responses in mechanical trauma // Complications of the early post-shock period of traumatic disease. - Leningrad, 1987. - P.43-52.
38. Sokolova T.F. Interaction of the central and immune systems in traumatic disease dynamics // Actual problems and perspectives of the modern reanimatology progress. - Moscow,1994. - P.63-65.
39. Sokolova T.F., Pospelov V.S. Thyroid hormones and specific immunity factors in rats subjected to severe mechanical trauma // Modern problems of clinical and experimental psychoneuroimmunology:The International symposium. - Tomsk,1992.- Vol.1. - P.108-111.
40. Sokolova T.F., Redkin Yu.V. A method of modelling of dosaged closed craniocerebral trauma in white rats // Zhurnal "Voprosy neirokhirurgii imeni N.N.Burdenko" ("N.N.Burdenko Journal Problems of neurosurgery"). - 1986. - N1. - P.62.
41. Sokolova T.F., Redkin Yu.V., Goryachev A.N. Efficiency of management of patients with severe secondary posttraumatic immunodeficiency // Rehabilitation of immune system:Abstracts of the International symposium. - Moscow,1990.- P.187.
42. Sokolova T.F., Fominykh S.G. Dalargine modulating effect on immunogenesis in posttraumatic anemia // Mezhdunarodnyi zhurnal po immunoreabilitatsii (International journal on immunorehabilitation). - 1994. - N1. - P.334.
43. Conjugation of immunity system components in iron deficiency / A.A.Golovin, Yu.V.Redkin, T.F.Sokolova e.a. // Gematologiya i transfuziologiya (Hematology and transfusiology). - 1993. - N5. - P.26-28.